Thor Vol 4 #1 by Jason Aaron and Russell Dauterman featured the first full appearance of a new Thor, later revealed to be the transformed Jane Foster. Since the news last night at San Diego Comic-Con that the upcoming Thor movie, Love And Thunder, would star Natalie Portman reprising her role as Jane Foster and starring as the new Thor, the prices on that storyline from the comic have been going bananas.
I've never been one to buy comics simply because I feel they'll be worth something later. Don't get me wrong, I understand the appeal. In fact, I have a close friend who does this and it's a skill in and of itself. I've just always been about the collecting aspect of it, particularly for books I kept following and enjoyed.
That said, I do own a first-print of this book and—if the book is going for $55 already—I'd consider offloading it if the price was right. I enjoyed the book but it's not one I continued to follow or feel compelled to hang on to.